Maram Abdel Nasser Taha Shtaya
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Background: We live in a universe that is being broken by hyperlipidemia, and, by not making anything concerning it, we are actually a part of the devastation. We let our lifetimes become loaded with unhealthy habits. So, yeah, no surprise you are tired of existence. If you desire to stop feeling exhausted of life, then originate a life that is worth living. Is this actually the life you desire? And, we have to become willing to alter how we see our life as a healthy life.
Hyperlipidemia is a medicinal expression for abnormally elevated levels of lipids/fats in the blood. Hyperlipidemia can be treated, but it’s oftentimes a life-long situation. You’ll demand to observe what you eat and also practice orderly. You might also demand to take a prescription medication. Anyway, I’d like to send to you the pharmacology flavor in Palestine by giving the trade names of drugs which are used in Palestine, to give students from the whole of world the chance to get a glimpse toward famous trade drugs in Palestine.
Course Questions and Aim: If lifestyle alterations aren’t enough to cure your hyperlipidemia, your physician may prescribe a medical treatment for you. This course aims to answer the following questions: What is the definition of hyperlipidemia? What are the Four Kinds of Lipoproteins? What does HDL cholesterol perform? What does LDL cholesterol perform? Lipids are travelled in the circulation packed in lipoproteins, but what’s about Lipoprotein Composition? What are the reasons of Hyperlipidemia? What are the lipid standards that must be preserved? What are the main groups of drugs which are used to treat hyperlipidemia? and What are Statins?
Significance of the Course: High triglyceride standards are believed to be a risk agent for increasing stiffness of the arteries (atherosclerosis illness) because many of triglyceride-consisting of lipoproteins that carry fat in the blood also carry cholesterol, a recognized contributor to atherosclerosis disease. Often, high triglyceride standards are found along with high cholesterol standards. This situation is indicated to as a combined Hyperlipidemia. Anyway, by knowing what are the main alterations to avoid and treat Hyperlipidemia, we are able to keep ourselves healthy.
Course Outline: This course consists of four sections. The First Section is a short background about Hyperlipidemia which supplies the following subtitles: 1) What is the definition of hyperlipidemia? 2) Reasons of Hyperlipidemia, 3) Management of Hyperlipidemia, 4) The Sequences of Hyperlipidemia, 5) Lipoprotein Composition and 6) What Are the Four Kinds of Lipoproteins? The Second Section is concerning the kinds of cholesterol, and it contains the following subtitles: 1) Triglycerides, 2) But what does HDL cholesterol perform? and 3) What does LDL cholesterol perform? The Third Section is concerning the Lipid Standards and The Fourth Section is concerning drugs which are utilized to lower Lipids standards and this section includes the following subtitles: 1) What are Statins? 2) Fibrates, and 3) Cholesterol Reuptake Inhibitor.
Discussion: There are two major kinds of cholesterol: low-density lipoprotein (LDL) and high-density lipoprotein (HDL). (Lipoproteins are composed of both fat and protein, and render as carriage for your cholesterol to journey through the bloodstream). Triglycerides are actually one of the kinds of fats (lipids) carried in the blood. Most of the body’s lipid is also stocked in the tissues as the shape of triglycerides.
In fact, HMG-CoA reductase inhibitors (statins) selectively block an enzyme named HMG-CoA reductase (3-hydroxy-3-methylglutaryl coenzyme A reductase) which is contributed in the composition of mevalonate, and this functions as a precursor of sterols containing cholesterol.
Fibric acid derivative medicines such as fenofibrate and gemfibrozil are most efficient in decreasing triglycerides, efficient in rising HDL level, and minimally efficient in decreasing LDL standards.
Nicotinic acid (Niacin), is most efficient in rising HDL level, efficient in decreasing triglycerides level, and mildly to moderately efficient in decreasing LDL standards. Omega-3 fatty acids have been offered to decrease triglyceride standards.
Results and Conclusions: Triglycerides are actually one of the kinds of fats (lipids) carried in the blood. Most of the body’s lipid is also stocked in the tissues as the shape of triglycerides. Triglyceride blood standards are generally measured with other lipid standards, such as cholesterol. However, elevated triglyceride standards can be caused by a set of illness procedures. Survey has presented that high standards of total apolipoprotein B, cholesterol, and LDL-cholesterol, are risk agents for enhancing cardiovascular illness.
Future Recommendation: This course aims to improve people knowledge toward the deleterious cholesterol levels. Doing so decreases your danger of heart ailments, stroke, heart attack, and other troubles. The target is to minimize the deleterious cholesterol levels. Doing so decreases your danger of harmful diseases. As known, Lipids are usually travelled in the circulation packed in lipoproteins. Diagnosis is formed via blood examination, so if you don’t examine, you won’t realize.
Key Words: Pharmacology, Hyperlipidemia, and Palestine
Instructors: Maram Abdel Nasser Taha Shtaya